NFL DFS, Cardinals vs. 49ers: DraftKings, FanDuel daily Fantasy football picks for Monday Night Football

Mexico City will host its fourth NFL game when the San Francisco 49ers meet the Arizona Cardinals on Monday Night Football. The Mexico fans should be in for a treat with playmakers like Christian McCaffrey, Deebo Samuel, George Kittle and DeAndre Hopkins decorating the field. They would all make for tantalizing NFL DFS picks for 49ers vs. Cardinals, but which NFL DFS sleepers should you seek for daily Fantasy football lineups on sites like DraftKings and FanDuel? Niners running back Elijah Mitchell could be a sneaky pick in the MNF NFL DFS player pool after he returned from injured reserve last week. He out-touched and out-produced McCaffrey in total yards, but will his volume sustain versus Arizona? Before you make your NFL DFS picks for Cardinals vs. 49ers on sites like DraftKings and FanDuel, be sure to check out the NFL DFS advice, strategy and projections from SportsLine daily Fantasy expert Mike McClure.

McClure is a legendary professional DFS player with over $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1% in more than a dozen other tournaments.

He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values ​​that he shares only with members at SportsLine.

This year, he’s already won the DraftKings Millionaire Maker twice and the FanDuel Million once. Now, McClure has turned his attention to Cardinals vs. 49ers and locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.

Top NFL DFS picks for Cardinals vs. 49ers

One of McClure’s top NFL DFS picks for Monday Night Football is Cardinals wide receiver Rondale Moore. The Purdue product was a second-round pick in the 2021 NFL Draft and caught 54 passes for 435 yards and a touchdown in his rookie season. He missed the first three games of the 2022 campaign with a hamstring injury, but has been a critical piece of the Arizona offense since returning to action.

Moore has been targeted at least eight times in five of the seven games he’s played and has played at least 86% of the snaps every week. Even with Hopkins back in the fold, he’s been targeted 31 times over the last three weeks, which has resulted in 24 catches for 255 yards and a score.

Part of McClure’s optimal NFL DFS strategy also includes rostering 49ers running back Christian McCaffrey. It’s been three games since the trade from Carolina and McCaffrey has played 112 snaps and been heavily involved in the offense. He’s had 55 touches during that span and turned those opportunities into 288 scrimmage yards, two rushing touchdowns, a receiving touchdown and a passing touchdown.

Even with McCaffrey facing competition for touches with Elijah Mitchell returning from a knee injury last week, McCaffrey was on the field 65% of the time while earning 14 carries and being targeted six times in the passing game. Expect McCaffrey to approach 20 touches again in Week 11 against an Arizona defense that he posted 25.8 points against in Week 4 with the Panthers. You can see the rest of McClure’s NFL DFS advice here.

How to make NFL DFS lineups for 49ers vs. Cardinals

McClure is also targeting another undervalued player who could explode for huge numbers on Monday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of McClure’s NFL DFS picks, at SportsLine.

Who is Mike McClure including in his optimal NFL DFS lineups for Monday Night Football? And which under-the-radar player is a must-roster? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a DFS expert who has won over $2 million with his daily Fantasy picks, and find out.

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